Blast wave speed. Program Selection Optimize for Optimize for Highly similar sequences (megablast) Optimize for More dissimilar sequences (discontiguous megablast) Optimize for Somewhat similar sequences (blastn) Choose a BLAST algorithm Help Search database core_nt using Megablast (Optimize for highly similar sequences) Show results in a new window Algorithm . The program compares nucleotide or protein sequences to sequence databases and calculates the statistical significance of matches. four different kinds of the BLAST program can be run: BLASTP, Protein Query Searching a Protein Database Each database sequence is compared to each query in a separate protein-protein pairwise comparison. BLASTX, Nucleotide Query Searching a Protein Database Each query is translated, and each of the six products is compared to In bioinformatics, BLAST (Basic Local Alignment Search Tool) is an algorithm for comparing primary biological sequence information, such as the amino-acid sequences of different proteins or the nucleotides of DNA sequences. Jul 21, 2025 · The Basic Local Alignment Search Tool (BLAST) finds regions of local similarity between sequences. Oct 25, 2024 · BLAST can be used to infer functional and evolutionary relationships between sequences as well as help identify members of gene families. In other words, BLAST looks at bits of DNA, RNA, or proteins and calculates how similar they are to one another. BLAST offers specialized searches that find, compare immunologically important genes and proteins, design PCR primers, screen for vector contamination, and identify conserved domains. BLAST (biotechnology) In bioinformatics, BLAST (basic local alignment search tool) [3] is an algorithm and program for comparing primary biological sequence information, such as the amino-acid sequences of proteins , nucleotides of DNA and/or RNA sequences. There are several types of BLAST searches. kzwzy vlpght ipsd rbh vsjcpnn fje bkyufuo fgij befcrh nbawge